
Testosterone enanthate injection USP, provides testosterone enanthate, a derivative of the primary endogenous androgen testosterone, for intramuscular administration. In their active form, androgens have a 17-beta-hydroxy group. Esterification of the 17-beta-hydroxy group increases the duration of action of testosterone; hydrolysis to free testosterone occurs in vivo. Testosterone esters are less polar than free testosterone. Testosterone esters in oil injected intramuscularly are absorbed slowly from the lipid phase; thus Testosterone Enanthate can be given at intervals of two to four weeks.
Testosterone enanthate used in males to treat primary hypogonadism (congenital or acquired) - testicular failure due to cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome, or orchidectomy. In females: metastatic mammary cancer. Other methods of counteracting estrogen activity in cases of adrenalectomy, hypophysectomy, and/or antiestrogen therapy.
Nandrolone decanoate is an injectable anabolic androgenic steroid. It is indicated for the management of the anemia of renal insufficiency and has been shown to increase hemoglobin and red cell mass. Nandrolone cannot be reduced by 5-alpha reductase into DHT and therefore does not have an adverse reaction on the prostate. Instead of DHT, nandrolone metabolizes into dihydronandrolone.
Nandrololone does not convert into estrogens. Nandrolone binds well to androgen receptors and also possesses non-receptor mediated stimulation on muscle growth. Nandrolone decanoate is one of the most potent anabolic steroid sfor muscle growth with an excellent myotrophic activity index 3.29–4.92. Nandrolone up-regulates androgen receptor AR expression in skeletal muscle, thus potentiating the actions of other steroids. Nandrolone does not have alkylation on the 17α-carbon and therefore is not toxic for the liver.
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